منابع مشابه
Dyspnea with hemoglobin SC disease.
BUMC PROCEEDINGS 2002;15:86–90 CASE PRESENTATION LINDA S. BANG, MD: A 41-year-old African American woman with sickle cell disease presented to the Baylor University Medical Center emergency department with dyspnea and dry cough for 3 weeks and back, leg, and chest pain for 2 to 3 days. The hemoglobin SC disease had been first diagnosed during pregnancy. Pleural tuberculosis with a left-sided ef...
متن کاملHemoglobin SC disease and proliferative retinopathy.
Retinopathy is one of the clinical signs of hemoglobin SC disease.1 It is often misunderstood and diagnosed late because it is initially asymptomatic due to its preferential localization in the periphery of the retina.2,3 A 25-year-old man from the Ivory Coast was admitted because of an abdominal pain crisis. The patient, who had sickle cell trait, had mild scleral jaundice and pronounced splen...
متن کاملElevated hypercoagulability markers in hemoglobin SC disease.
Hemoglobin SC disease is a very prevalent hemoglobinopathy; however, very little is known about this condition specifically. There appears to be an increased risk of thromboembolic events in hemoglobin SC disease, but studies evaluating the hemostatic alterations are lacking. We describe the findings of a cross-sectional observational study evaluating coagulation activation markers in adult pat...
متن کاملMolecular and cellular pathogenesis of hemoglobin SC disease.
Solution and cell studies were performed to ascertain why individuals with hemoglobin (Hb) SC have disease whereas those with Hb AS do not. The polymerization of deoxygenated mixtures containing sickle cell Hb (Hb S; alpha 2 beta 2(6)Glu leads to Val) and Hb C (alpha 2 beta 2(6)Glu leads to Lys) was investigated by measurements of delay times and solubilities. In mixtures containing more than 4...
متن کاملDual Case Report of Hemoglobin SC Disease in Pregnancy
Heterozygous hemoglobin sickle cell disease (HbSC) is the second most frequent hemoglobinopathy behind SCA [1]. Individuals with HbSC are heterozygous having received the βC-gene for hemoglobin C from one parent and the βS-gene for hemoglobin S from the other parent [2,3]. HbSC red cells contain equal levels of HbS and HbC. The blood smears of individuals with HbSC contain primarily Target cell...
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ژورنال
عنوان ژورنال: American Journal of Hematology
سال: 1997
ISSN: 0361-8609,1096-8652
DOI: 10.1002/(sici)1096-8652(199704)54:4<313::aid-ajh9>3.3.co;2-u